Antioxidant Supplements and Simvastatin-Niacin Therapy
نویسندگان
چکیده
منابع مشابه
Antioxidant supplements and simvastatin-niacin therapy.
Simvastatin-Niacin Therapy To the Editor: This article1 attracted our attention first because of the wide implications and second because of the related editorial comments2 that sort of urged the physicians to “stop prescribing antioxidant vitamins to prevent and treat heart disease.” In these studies, subjects with coronary artery disease were divided into 4 treatment groups, namely (1) placeb...
متن کاملAntioxidant Supplements and Simvastatin-Niacin Therapy
Simvastatin-Niacin Therapy To the Editor: This article1 attracted our attention first because of the wide implications and second because of the related editorial comments2 that sort of urged the physicians to “stop prescribing antioxidant vitamins to prevent and treat heart disease.” In these studies, subjects with coronary artery disease were divided into 4 treatment groups, namely (1) placeb...
متن کاملAntioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL.
One strategy for treating coronary artery disease (CAD) patients with low HDL cholesterol (HDL-C) is to maximally increase the HDL-C to LDL-C ratio by combining lifestyle changes with niacin (N) plus a statin. Because HDL can prevent LDL oxidation, the low-HDL state also may benefit clinically from supplemental antioxidants. Lipoprotein changes over 12 months were studied in 153 CAD subjects wi...
متن کاملNiacin Extended Release (ER)/Simvastatin (Simcor®)
Oral fixed-dose niacin extended release/simvastatin is associated with clinically relevant improvements in plasma lipid profiles, including lowering of non-high-density lipoprotein cholesterol levels, relative to simvastatin monotherapy in patients with mixed dyslipidemias who had not responded fully to simvastatin monotherapy, and is generally well tolerated.
متن کاملAntioxidant supplements and mortality.
To the Editor: Based on their meta-analysis of antioxidant supplementation trials, Dr Bjelakovic and colleagues 1 conclude that some of the intervention nutrients appeared to be associated with increased mortality. Particular aspects of their approach, analysis, and reported findings may have led to incomplete or biased determinations of the real effect of such nutrients in various populations....
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2001
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvb.21.12.2099